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Twelve patients reported minor adverse effects, consisting of drowsiness, arthralgia and bone aches, dyspnea, headache, nausea, and blurred vision. The adverse effects were mostly reported at the first follow-up and were easily tolerated.

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Unfortunately, no details of adverse effects were given. There was no recurrence after follow-up of 4 months.

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One patient had nausea and vomiting 3 hours after the first dose and again after the second dose, but they were transient and required no therapy. In four patients there were mild laboratory abnormalities slight increases in liver function tests in two, microscopic hematuria in one, and mild leukopenia and lymphocytosis in one.



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